BRIEF

on The Vanguard Group, Inc. (isin : US12572Q1058)

The Vanguard Group's Position in Mural Oncology Revealed

The Vanguard Group, Inc. has disclosed its position in Mural Oncology plc, as per the Irish Takeover Panel's regulations. The disclosure reveals an interest amounting to 1.67% in $0.01 ordinary shares, totaling 288,715 securities. The data is accurate as of November 5, 2025.

The disclosure confirms that there are no cash-settled derivatives or stock-settled derivatives in relation to Mural Oncology. Furthermore, recent transactions include a purchase of 32 ordinary shares at $2.09 each.

No indemnity or option arrangements or any formal or informal agreements relating to these securities or derivatives are in place. Consequently, there is no Supplemental Form 8 attached to the disclosure, and no other parties are involved in this declaration.

R. H.

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